Molecular dynamics simulation and docking analysis of NF-κB protein binding with sulindac acid
| Autor: | Shaban, Ahmad, Piyush, Bhanu, Jitendra, Kumar, Ravi Kant, Pathak, Dharmendra, Mallick, Akshay, Uttarkar, Vidya, Niranjan, Vachaspati, Mishra |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Bioinformation. 18:170-179 |
| ISSN: | 0973-2063 0973-8894 |
| DOI: | 10.6026/97320630018170 |
| Popis: | It is of interest to document the Molecular Dynamics Simulation and docking analysis of NF-κB target with sulindac sodium in combating COVID-19 for further consideration. Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid class that is marketed by Merck under the brand name Clinoril. We show the binding features of sulindac sodium with NF-κB that can be useful in drug repurposing in COVID-19 therapy. |
| Databáze: | OpenAIRE |
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