Scoping Review of Six Retrospective Studies: Risk Factors Associated With the Case Fatality Rate of People Infected With Coronavirus (COVID-19)

Autor: AsimAhmed Elnour, Adel Sadeq, FarahHamad Farah, Azza Ramadan, Judit Don, AhmedIbrahim Fathelrahman, Maisoun Alkaabi, Mohammed Baraka, AbubakarB Abubakar, SashaMohammed Elamin Suliman, Abdulla Al Amoodi, IsraaYousif Khidir, KhalidAwad Al Kubaisi, Nadia Al Mazroui
Rok vydání: 2021
Předmět:
Zdroj: Journal of pharmacybioallied sciences. 14(2)
ISSN: 0976-4879
Popis: It would be rational to describe the pattern of the clinical characteristics of the survivors and the nonsurvivors during the critical intensive-infection era of coronavirus disease 2019 (COVID-19). The explicit objective of the current scoping review was to delineate the predictive risk factors associated with case fatality rate (CFR).Six retrospective studies of subjects infected with COVID-19 published between December 1, 2020, and March 30, 2020, describing nonsurvivors in Wuhan/Hubei, China, were identified.There were 1769 subjects with a mean age of 52 years, and 65.9% were male. The highest comorbidity reported was cardiovascular diseases at 22.2% (393/1769). The overall number of cases admitted to the intensive care unit was 228 (12.9%). The reported overall CFR was 7.7% (136/1769), with the highest at 28.2% (54/191), and the lowest at 1.4% (15/1099). The mean duration of onset until death for nonsurvivors was 15.3 days.We have found that older age, male gender, the longer duration from onset till death (days), development of acute respiratory distress syndrome/shock, preexisting diabetes, and preexisting cardiovascular diseases were the major risk factors associated with high CFR.
Databáze: OpenAIRE