Megaloblastic anemia in children: case series from a single institution and literature review

Autor:	Andreea Oltean, Mihaela Ioana Chincesan, Maria Despina Baghiu, Eniko Molnar, Cristina Oana Marginean
Rok vydání:	2018
Předmět:	megaloblasts Pediatrics medicine.medical_specialty Series (stratigraphy) business.industry vitamin b12 General Medicine medicine.disease RJ1-570 folic acid megaloblastic anemia hemic and lymphatic diseases medicine Medicine Single institution business Megaloblastic anemia
Zdroj:	Romanian Journal of Pediatrics, Vol 67, Iss 4, Pp 171-176 (2018)
ISSN:	2069-6175 1454-0398
Popis:	Folic acid and cobalamin are B-group vitamins that play an essential role in many cellular processes. Deficiency in one or both of these vitamins causes megaloblastic anemia, a very rare anemia in children, which is characterized by the presence of megaloblasts. Vitamin B12 deficiency can be caused by a low intake, decreased absorption, or impaired use. We present five cases of megaloblastic anemia that illustrate the onset of anemia at different ages and in different pathologies. We concluded that megaloblastic anemia is a rare anemia diagnosed in children, with multiple causes, occurring in the context of a vegetarian diet, or associated with an autoimmune disease, protein-calorie malnutrition of the mother during pregnancy and megaloblastic anemia of the mother associated with lack of substitution during pregnancy and during breastfeeding.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87bb372f0e54ae5ea19e8300206db106 https://doi.org/10.37897/rjp.2018.4.2 Zobrazit plný text záznamu Plný text ve formátu PDF