BK Virus Pneumonia with CMV Colitis in a Kidney Transplant Recipient: Successful Treatment with Non-Cidofovir Based Therapy
| Autor: | Amal Hamieh, Hussein Karnib, Mouhamad Nasser, Ali R. Chaitou |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty viruses 030106 microbiology Pharmaceutical Science medicine.disease_cause Gastroenterology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Health Care Sciences and Services Internal medicine medicine Pharmacology (medical) 030212 general & internal medicine Colitis Sağlık Bilimleri ve Hizmetleri Kidney transplantation Leflunomide business.industry BK virus pneumonia CMV colitis Kidney transplantation Leflunomide Ciprofloxacin virus diseases biochemical phenomena metabolism and nutrition medicine.disease BK virus Kidney transplant recipient Ciprofloxacin Pneumonia Complementary and alternative medicine chemistry business Cidofovir medicine.drug |
| Zdroj: | Volume: 11, Issue: 01 36-41 Journal of Microbiology and Infectious Diseases |
| ISSN: | 2146-3158 2146-9369 |
| Popis: | BK virus (BKV) pneumonia is a rare entity especially seen in immunosuppressed patients, for which cidofovir is the used treatment option. We describe a case of a young female patient who presented for altered kidney function six months following kidney transplantation for focal segmental glomerulosclerosis and was found to have BKV nephritis. Her in-hospital stay was complicated by BKV pneumonia requiring mechanical ventilation, in addition to CMV colitis. She was treated with leflunomide/ciprofloxacin and ganciclovir for her pneumonia and colitis, respectively. The patient improved clinically except that her kidney function deteriorated. Leflunomide/ciprofloxacin combination may constitute an effective and safe alternative to cidofovir for the treatment of BKV pneumonia, in particular when cidofovir is not available. J Microbiol Infect Dis 2021; 11(1):36-41. |
| Databáze: | OpenAIRE |
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