Influence of cadmium, lead, and zinc on the ability of sensitized guinea pig lymphocytes to interact with specific antigen and to produce lymphokine
| Autor: | Jack Schwartz, L. Kiremidjian-Schumacher, Robert A. Dickstein, G. Stotzky, Vinay Likhite |
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| Rok vydání: | 1981 |
| Předmět: |
Male
Cell Guinea Pigs chemistry.chemical_element Spleen Zinc Biochemistry Guinea pig Antigen medicine Animals Lymphocytes Antigens General Environmental Science Cadmium Lymphokines biology Lymphokine Exudates and Transudates respiratory system Molecular biology Ovalbumin medicine.anatomical_structure chemistry Lead Metals biology.protein Female |
| Zdroj: | Environmental research. 24(1) |
| ISSN: | 0013-9351 |
| Popis: | The effects of cadmium, lead, and zinc on the ability of sensitized guinea pig spleen lymphocytes to interact with an antigen (ovalbumin) and to produce migration inhibitory factor (MIF) were studied by cell electrophoresis and migration inhibition of macrophages. The metals (Cd > Zn > Pb) significantly interfered with the interaction between the antigen and the surface of sensitized lymphocytes and also inhibited the production of MIF. |
| Databáze: | OpenAIRE |
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