Dipivalyl Epinephrine: A New Pro-Drug in the Treatment of Glaucoma
Autor: | Abbas E. Kitabchi, Alan I. Mandell, Frankie B. Stentz |
---|---|
Rok vydání: | 1978 |
Předmět: |
medicine.medical_specialty
Epinephrine genetic structures Thin layer Glaucoma Pharmacology Aqueous Humor Cornea chemistry.chemical_compound Dipivalyl epinephrine Internal medicine medicine Humans Carbon Radioisotopes Dipivefrin business.industry Dansyl chloride Prodrug medicine.disease eye diseases Ophthalmology medicine.anatomical_structure Endocrinology chemistry Autoradiography Chromatography Thin Layer sense organs business medicine.drug |
Zdroj: | Ophthalmology. 85:268-275 |
ISSN: | 0161-6420 |
DOI: | 10.1016/s0161-6420(78)35668-2 |
Popis: | The dansyl chloride technique in conjunction with thin layer chromatography and autoradiography has shown that dipivalyl epinephrine is a pro-drug in the human eye. Dipivalyl epinephrine appears to be a more effective epinephrine compound, in that it penetrates the cornea approximately 17 times greater than epinephrine. |
Databáze: | OpenAIRE |
Externí odkaz: |