Biological agents: investigation into leprosy and other infectious diseases before indication
| Autor: | Ana Regina Franchi Travolo, João Roberto Antonio, Vania Del Arco Paschoal, Rosa Maria Cordeiro Soubhia, Carolina Forte Amarante |
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| Rok vydání: | 2013 |
| Předmět: |
Male
medicine.medical_specialty Tuberculosis Biopsy Case Report Dermatology Disease Arthritis Rheumatoid Biological Factors Psoriatic arthritis Recurrence Leprosy Psoriasis Exposure to biological agents medicine Humans Rheumatoid arthritis Ankylosing spondylitis Tumor Necrosis Factor-alpha business.industry Antibodies Monoclonal Middle Aged medicine.disease Infliximab RL1-803 Antirheumatic Agents Immunology Syphilis business |
| Zdroj: | Anais Brasileiros de Dermatologia Anais Brasileiros de Dermatologia, Vol 88, Iss 6 suppl 1, Pp 23-25 (2013) |
| ISSN: | 0365-0596 |
| DOI: | 10.1590/abd1806-4841.20132187 |
| Popis: | Biological agents are widely used for various immune-mediated diseases, with remarkable effectiveness in the treatment of rheumatoid arthritis (RA), psoriasis, psoriatic arthritis, ankylosing spondylitis and Crohn's disease. However, attention needs to be drawn to the adverse effects of these therapies and the risk of reactivating underlying granulomatous infectious diseases such as tuberculosis, leprosy, syphilis, leishmaniasis, among others. The objective of this paper is to describe a case of leprosy in a patient with RA using anti-TNF alfa, demonstrating the need for systematic investigation of skin lesions suggestive of leprosy in patients who require rheumatoid arthritis therapeutic treatment, especially in endemic regions like Brazil. |
| Databáze: | OpenAIRE |
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