Influence of Intradialytic Aerobic Training in Cerebral Blood Flow and Cognitive Function in Patients with Chronic Kidney Disease: A Pilot Randomized Controlled Trial
Autor: | Barbara Perez Vogt, Fernanda Stringuetta Belik, Jacqueline Costa Teixeira Caramori, Viviana Rugolo Oliveira e Silva, Rodrigo Bazan, Paulo José Fortes Villas Boas, Roberto Jorge da Silva Franco, Renato de Souza Gonçalves, Luis Cuadrado Martin, João Carlos Hueb, Pasqual Barretti, Gabriel Pereira Braga |
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Přispěvatelé: | Universidade Estadual Paulista (Unesp) |
Rok vydání: | 2018 |
Předmět: |
Adult
Male medicine.medical_specialty Ultrasonography Doppler Transcranial medicine.medical_treatment Population 030232 urology & nephrology Pilot Projects law.invention 03 medical and health sciences Cognition 0302 clinical medicine Randomized controlled trial Renal Dialysis law Chronic kidney disease Internal medicine medicine Humans Aerobic exercise Renal Insufficiency Chronic education Exercise Aged education.field_of_study Physical activity business.industry Cerebral arteries Blood flow Middle Aged medicine.disease Exercise Therapy Cerebral blood flow Hemodialysis Cerebrovascular Circulation Exercise Test Female Cognition Disorders business 030217 neurology & neurosurgery Kidney disease |
Zdroj: | Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP |
ISSN: | 2235-3186 1660-8151 |
Popis: | Made available in DSpace on 2018-12-11T17:20:43Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-08-01 Background and Objectives: Changes in cerebral blood flow may play an important role in cognitive impairment among hemodialysis (HD) patients. Physical activity has a promising role in delaying cognitive impairment in general population, but there are only a few studies in HD to confirm this finding. We aimed to evaluate the effects of intradialytic aerobic training on cerebral blood flow and cognitive impairment in HD. Design, Setting, Participants, and Measurements: This is a pilot, controlled, randomized trial. Fifteen patients underwent intradialytic aerobic training 3 times a week for 4 months. The control group was comprised of another 15 patients. Results: Trained patients had a statistically significant improvement of cognitive impairment and basilar maximum blood flow velocity. The proportion of arteries with increased flow velocity was statistically significant between groups. Conclusions: Intradialytic aerobic training improves cognitive impairment and cerebral blood flow of patients in HD, suggesting a possible mechanism improving cognitive impairment by physical training in HD. These data still need to be confirmed by major trials. Division of Nephrology Department of Internal Medicine Botucatu Medical School São Paulo State University (UNESP) Division of Nephrology Department of Internal Medicine Botucatu Medical School São Paulo State University (UNESP) |
Databáze: | OpenAIRE |
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