Influence of Intradialytic Aerobic Training in Cerebral Blood Flow and Cognitive Function in Patients with Chronic Kidney Disease: A Pilot Randomized Controlled Trial

Autor: Barbara Perez Vogt, Fernanda Stringuetta Belik, Jacqueline Costa Teixeira Caramori, Viviana Rugolo Oliveira e Silva, Rodrigo Bazan, Paulo José Fortes Villas Boas, Roberto Jorge da Silva Franco, Renato de Souza Gonçalves, Luis Cuadrado Martin, João Carlos Hueb, Pasqual Barretti, Gabriel Pereira Braga
Přispěvatelé: Universidade Estadual Paulista (Unesp)
Rok vydání: 2018
Předmět:
Zdroj: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
ISSN: 2235-3186
1660-8151
Popis: Made available in DSpace on 2018-12-11T17:20:43Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-08-01 Background and Objectives: Changes in cerebral blood flow may play an important role in cognitive impairment among hemodialysis (HD) patients. Physical activity has a promising role in delaying cognitive impairment in general population, but there are only a few studies in HD to confirm this finding. We aimed to evaluate the effects of intradialytic aerobic training on cerebral blood flow and cognitive impairment in HD. Design, Setting, Participants, and Measurements: This is a pilot, controlled, randomized trial. Fifteen patients underwent intradialytic aerobic training 3 times a week for 4 months. The control group was comprised of another 15 patients. Results: Trained patients had a statistically significant improvement of cognitive impairment and basilar maximum blood flow velocity. The proportion of arteries with increased flow velocity was statistically significant between groups. Conclusions: Intradialytic aerobic training improves cognitive impairment and cerebral blood flow of patients in HD, suggesting a possible mechanism improving cognitive impairment by physical training in HD. These data still need to be confirmed by major trials. Division of Nephrology Department of Internal Medicine Botucatu Medical School São Paulo State University (UNESP) Division of Nephrology Department of Internal Medicine Botucatu Medical School São Paulo State University (UNESP)
Databáze: OpenAIRE