Treatment with indigo plant (Polygonum tinctorium Lour) improves serum lipid profiles in Wistar rats fed a high-fat diet
| Autor: | Tohru Sakai, Maki Kondo, Tasuku Takino, Wataru Odani, Hiroko Tsuji, Risako Takeda |
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| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Blood lipids Diet High-Fat General Biochemistry Genetics and Molecular Biology Indigo 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Internal medicine medicine Animals Rats Wistar Polygonum tinctorium Cholesterol Body Weight Significant difference Polyphenols General Medicine medicine.disease Lipids Obesity Rats Endocrinology 030228 respiratory system Fat diet chemistry 030220 oncology & carcinogenesis embryonic structures Metabolic rate Polygonum Energy Metabolism |
| Zdroj: | The Journal of Medical Investigation. 67:158-162 |
| ISSN: | 1349-6867 1343-1420 |
| DOI: | 10.2152/jmi.67.158 |
| Popis: | We investigated the effects of Polygonum tinctorium Lour (PTL), a plant commonly known as indigo, on biological parameters in an animal model of high-fat diet-induced obesity. Wistar rats fed a high-fat diet and treated with PTL showed lower serum levels of triglycerides and total cholesterol levels and a higher serum levels of HDL cholesterol than those in Wistar rats fed a high-fat diet without PTL treatment. The weight of mesenteric fat in PTL-treated rats was decreased compared to that in control rats not treated with PTL. In addition, energy metabolic rate in the dark period, but not in the light period, in PTL-treated rats was higher than that in control rats. Although a significant difference was not observed, body weight in PTL-treated rats tended to be decreased compared to that in control rats. The results show that PTL improves serum lipid profiles in Wistar rats with high-fat diet-induced obesity. J. Med. Invest. 67 : 158-162, February, 2020. |
| Databáze: | OpenAIRE |
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