Novel CCR1 antagonists with improved metabolic stability

Autor:	Poss Christopher Stanley, Molly A. McGlynn, Truesdell Susan Jane, Maryrose J. Conklyn, Suzanne S Krueger, William H. Brissette, Matthew Frank Brown, Timothy J. Strelevitz, Timothy Joseph Paradis, Kwansik Yoon, John Charles Kath, Eric B. McElroy, Mike Avery, Richard M. Shepard, Michelle Rossulek, Laurie Tylaska, Jeff Sims, Kevin Colizza, Ronald P. Gladue, Deye Zheng, Greg D. Lundquist, Erin N Mairs, Amy P DiRico, Brett M. Lillie, Paul D. Lira, J.H Chang
Rok vydání:	2004
Předmět:	CCR1 Chemistry Organic Chemistry Clinical Biochemistry Receptors CCR1 Pharmaceutical Science Biological activity Haplorhini Metabolic stability Biochemistry Chemical synthesis In vitro Dogs Pharmacokinetics In vivo Drug Discovery Molecular Medicine Animals Receptors Chemokine Molecular Biology
Zdroj:	Bioorganicmedicinal chemistry letters. 14(9)
ISSN:	0960-894X
Popis:	The synthesis, biological activity, and pharmacokinetic profile of novel CCR1 antagonists are described.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8796dcf1eb5be0c84b0970136c821e02 https://pubmed.ncbi.nlm.nih.gov/15081003 Zobrazit plný text záznamu Full Text from ScienceDirect