One-year mortality increases four-fold in frail patients undergoing cardiac surgery
| Autor: | Christian H Møller, Ulver Spangsberg Lorenzen, Mads Hornum, Caroline Bäck, Peter Skov Olsen, Morten Jørgensen |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male medicine.medical_specialty Population ageing Time Factors Frail Elderly 030204 cardiovascular system & hematology Risk Assessment One year mortality 03 medical and health sciences 0302 clinical medicine Postoperative Complications Risk Factors Internal medicine medicine Humans Prospective Studies Cardiac Surgical Procedures Geriatric Assessment Aged Framingham Risk Score business.industry General Medicine Odds ratio Confidence interval Cardiac surgery Clinical trial Treatment Outcome 030228 respiratory system Surgery Observational study Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery. 59(1) |
| ISSN: | 1873-734X |
| Popis: | OBJECTIVES An increased focus on biological age, ‘frailty’, is important in an ageing population including those undergoing cardiac surgery. None of the existing surgery risk scores European System for Cardiac Operative Risk Evaluation II or Society of Thoracic Surgeons score incorporates frailty. Therefore, there is a need for an additional risk score model including frailty and not simply the chronological age. The aim of this study was to evaluate the impact of frailty assessment on 1-year mortality and morbidity for patients undergoing cardiac surgery. METHODS A total of 604 patients aged ≥65 years undergoing non-acute cardiac surgery were included in this single-centre prospective observational study. We compared 1-year mortality and morbidity in frail versus non-frail patients. The Comprehensive Assessment of Frailty (CAF) score was used: This is a score of 1–35 determined via minor physical tests. A CAF score ≥11 indicates frailty. RESULTS The median age was 73 years and 79% were men. Twenty-five percent were deemed frail. Frail patients had four-fold, odds ratios 4.63, 95% confidence interval (CI) 2.21–9.69; P CONCLUSIONS CAF score identified frail patients undergoing cardiac surgery and was a good predictor of 1-year mortality. Clinical trial registration number NCT02992587. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|