Blood viscosity and optimal hematocrit in narrow tubes
| Autor: | Eugen P Zilow, Achim A Stadler, Otwin Linderkamp |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Fåhræus–Lindqvist effect
Adult medicine.diagnostic_test Physiology Chemistry Fåhræus effect Blood viscosity Oxygen transport Mineralogy Polycythemia Hematocrit Blood Viscosity Models Biological Oxygen Viscosity Rheology hemic and lymphatic diseases Physiology (medical) medicine Humans Tube (fluid conveyance) circulatory and respiratory physiology Biomedical engineering |
| Zdroj: | Biorheology. 27(5) |
| ISSN: | 0006-355X |
| Popis: | Blood viscosity in normal adults was measured in glass tubes with diameters of 50, 100 and 500 microns for a wide range of adjusted feed hematocrits (15-70%). Blood viscosity decreased at each of the adjusted feed hematocrits when going from a 500-micron tube to a 50-micron tube. The viscosity reduction increased with increasing hematocrit. The steepness in the hematocrit-viscosity curves decreased with decreasing tube diameter. Erythrocyte transport efficiency (hematocrit/blood viscosity) was calculated to estimate the optimal hematocrit for oxygen transport. Optimal hematocrit averaged 38% in 500-micron tubes, 44% in 100-micron tubes and 51% in 50-micron tubes. Our results suggest that the strong Fahraeus-Lindqvist effect at high hematocrits may help to maintain oxygen transport in polycythemic patients as long as the driving pressure is sufficient. |
| Databáze: | OpenAIRE |
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