Eveningness chronotype preference among individuals at clinical high risk for psychosis

Autor: Jessica R. Lunsford-Avery, Vijay A. Mittal, Stephanie A. Korenic, Jason Schiffman, Lauren M. Ellman, Andrea Pelletier-Baldelli, Leah Jackson
Rok vydání: 2021
Předmět:
Zdroj: Schizophr Res
ISSN: 0920-9964
DOI: 10.1016/j.schres.2021.07.034
Popis: BACKGROUND: Circadian rhythm disturbances are frequently implicated in psychosis. Indeed, research has suggested several avenues by which circadian rhythms may play a mechanistic role as well as contribute to clinical outcomes. Despite its potential role as a risk factor, little is known about circadian rhythm disruption among individuals at clinical high risk (CHR) for psychosis, clinical correlates, or specificity to the psychosis risk syndrome. METHODS: Eighty-four CHR, 74 individuals with depressive disorders (DD), and 101 non-psychiatric controls (NPC) participated in structured clinical interviews and provided self-reports of chronotype preference. Clinical (positive, negative, anxious, and depressive symptoms) and social functioning outcomes were self-reported and/or clinician-rated. Analyses of covariance controlling for demographics examined group differences in chronotype preference, and partial Pearson correlations evaluated associations with clinical/functional outcomes. RESULTS: Group differences were observed (F(11, 246)=8.05, p
Databáze: OpenAIRE