Type IV hypersensitivity reactions following Dermabond adhesive utilization in knee surgery: A Report of Three Cases
Autor: | Hien Pham, Laith M. Jazrawi, Eric J. Strauss, Michelle Yagnatovsky, Andrew S. Rokito |
---|---|
Rok vydání: | 2017 |
Předmět: |
Adult
Male medicine.medical_specialty Physical Therapy Sports Therapy and Rehabilitation Knee Injuries 02 engineering and technology Infections law.invention Diagnosis Differential 030207 dermatology & venereal diseases 03 medical and health sciences Postoperative Complications 0302 clinical medicine law Adhesives medicine Humans Hypersensitivity Delayed Orthopedic Procedures Orthopedics and Sports Medicine Cyanoacrylates Retrospective Studies Sutures business.industry 021001 nanoscience & nanotechnology medicine.disease Surgery Type IV hypersensitivity Hypersensitivity reaction Cyanoacrylate Delayed hypersensitivity Knee surgery Female Tissue Adhesives Septic arthritis Allergists 0210 nano-technology Complication business |
Zdroj: | The Physician and Sportsmedicine. :1-4 |
ISSN: | 2326-3660 0091-3847 |
DOI: | 10.1080/00913847.2017.1283208 |
Popis: | We retrospectively reviewed the records of 3 patients (3 knees) with a delayed type hypersensitivity reaction following Dermabond exposure after an orthopaedic knee procedure. Delayed hypersensitivity reactions are mediated by CD4+ helper T cells. The use of skin adhesives in place of traditional sutures is increasing in popularity given Dermabond's potential benefits of decreased wound infection rate and better wound approximation. However, hypersensitivity reactions to the cyanoacrylate material in Dermabond have been described. Differentiating hypersensitivity reactions from post-operative infections is important as septic arthritis is a potentially devastating complication. This case series presents the challenge of properly diagnosing and managing hypersensitivity reactions. Consultation with allergists and dermatologists may be appropriate for ascertaining the nature of the surgical site complication and proper management. The recommended management of hypersensitivity-type reactions is a course of topical steroids and infection work up if needed. |
Databáze: | OpenAIRE |
Externí odkaz: |