Bilayer structures in dioctadecyldimethylammonium bromide/oleic acid dispersions

Autor: Sylwia Kedracka-Krok, Mariusz Kepczynski, Jan Bednar, Joanna Lewandowska, Karolina Witkowska, Veronika Mistrikova, Maria Nowakowska, Paweł Wydro
Přispěvatelé: Faculty of Chemistry, Uniwersytet Jagielloński w Krakowie = Jagiellonian University (UJ), Laboratoire de Spectrométrie Physique (LSP), Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS)
Rok vydání: 2011
Předmět:
DODAB
Isothermal microcalorimetry
MESH: Viscosity
Lipid Bilayers
Analytical chemistry
02 engineering and technology
010402 general chemistry
Mole fraction
01 natural sciences
Biochemistry
Microviscosity
MESH: Quaternary Ammonium Compounds
chemistry.chemical_compound
Differential scanning calorimetry
Microscopy
Electron
Transmission
Bromide
Microscopy
Interference
Langmuir monolayer
MESH: Microscopy
Interference
Molecular Biology
vesicles
[SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry
Molecular Biology/Structural Biology [q-bio.BM]
Calorimetry
Differential Scanning
Viscosity
Chemistry
MESH: Lipid Bilayers
Bilayer
Vesicle
MESH: Calorimetry
Differential Scanning
MESH: Oleic Acid
Organic Chemistry
Cell Biology
cryo-transmission electron microscopy
021001 nanoscience & nanotechnology
microcalorimetry
0104 chemical sciences
Quaternary Ammonium Compounds
Membrane
MESH: Microscopy
Electron
Transmission
Thermodynamics
MESH: Thermodynamics
0210 nano-technology
Oleic Acid
Zdroj: Chemistry and Physics of Lipids
Chemistry and Physics of Lipids, Elsevier, 2011, 164 (5), pp.359-67. ⟨10.1016/j.chemphyslip.2011.04.007⟩
ISSN: 0009-3084
DOI: 10.1016/j.chemphyslip.2011.04.007
Popis: International audience; This paper reports on the properties of bilayers composed of dioctadecyldimethylammonium bromide (DODAB) and oleic acid (OA) at various molar ratios. The mole fraction of OA, X(OA), was varied in the range of 0-1 and the total lipid content was constant and equal to 10 mM. The DODAB/OA dispersions were extruded at a temperature higher than that of the gel-liquid transition of DODAB. The morphology of bilayer structures formed in the dispersions was inspected using a cryogenic transmission electron microscopy (cryo-TEM) and a differential interference contrast microscopy (DIC). The observations revealed that the incorporation of OA into DODAB bilayer results in a decrease of the membrane curvature. Anisotropy measurements using 1,6-diphenylhexatriene (DPH) as a rotator probe demonstrated that the DODAB/OA membrane microviscosity decreased considerably for X(OA)>0.4. The thermal behavior of DODAB/OA membranes has been studied by differential scanning calorimetry (DSC). In the case of the systems in which X(OA)
Databáze: OpenAIRE
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