Invasive motor cortex stimulation influences intracerebral structures in patients with neuropathic pain: An activation likelihood estimation meta-analysis of imaging data

Autor: Kris Vissers, Robert van Dongen, Maudy van der Heiden, Dennis J.L.G. Schutter, Dylan J H A Henssen, Esmay Giesen, Sibylle Lange, Erkan Kurt, Mijke Kerperien, Ruben Volkers
Rok vydání: 2020
Předmět:
efficacy
Inferior frontal gyrus
Electric Stimulation Therapy
Review Article
Ventral lateral nucleus
Healthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18]
03 medical and health sciences
0302 clinical medicine
Gyrus
medicine
Humans
Review Articles
Default mode network
Likelihood Functions
business.industry
Action
intention
and motor control
Putamen
Other Research Radboud Institute for Health Sciences [Radboudumc 0]
Motor Cortex
Precentral gyrus
General Medicine
Medial frontal gyrus
Cerebral blood flow
Anesthesiology and Pain Medicine
medicine.anatomical_structure
Neurology
Superior frontal gyrus
nervous system
meta‐analysis
Cerebrovascular Circulation
Neuralgia
Neurology (clinical)
chronic neuropathic pain
business
Neuroscience
030217 neurology & neurosurgery
motor cortex stimulation
Zdroj: Neuromodulation, 23, 436-443
Neuromodulation, 23, 4, pp. 436-443
Neuromodulation
ISSN: 1094-7159
Popis: Contains fulltext : 219586.pdf (Publisher’s version ) (Open Access) Objective: Invasive motor cortex stimulation (iMCS) has been proposed as a treatment for intractable neuropathic pain syndromes. Although the mechanisms underlying the analgesic effect of iMCS remain largely elusive, several studies found iMCS-related changes in regional cerebral blood flow (rCBF) in neuropathic pain patients. The aim of this study was to meta-analyze the findings of neuroimaging studies on rCBF changes to iMCS. Methods: PubMed, Embase, MEDLINE, Google Scholar, and the Cochrane Library were systematically searched for retrieval of relevant scientific papers. After initial assessment of relevancy by screening title and abstract by two investigators, independently, predefined inclusion and exclusion criteria were used for final inclusion of papers. Descriptive results were statistically assessed, whereas coordinates were pooled and meta-analyzed in accordance with the activation likelihood estimation (ALE) methodology. Results: Six studies were included in the systematic narrative analysis, suggesting rCBF increases in the cingulate gyrus, thalamus, insula, and putamen after switching the MCS device "ON" as compared to the "OFF" situation. Decreases in rCBF were found in for example the precentral gyrus and different occipital regions. Two studies did not report stereotactic coordinates and were excluded from further analysis. ALE meta-analysis showed that, after switching the iMCS electrode "ON," increased rCBF occurred in the (1) anterior cingulate gyrus; (2) putamen; (3) cerebral peduncle; (4) precentral gyrus; (5) superior frontal gyrus; (6) red nucleus; (7) internal part of the globus pallidus; (8) ventral lateral nucleus of the thalamus; (9) medial frontal gyrus; (10) inferior frontal gyrus; and (11) claustrum, as compared to the "OFF" situation. Reductions in rCBF were found in the posterior cingulate gyrus when the iMCS electrode was turned "OFF." Conclusions: These findings suggested that iMCS induces changes in principal components of the default mode-, the salience-, and sensorimotor network. 8 p.
Databáze: OpenAIRE
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