Association between ulcerative colitis and systemic lupus erythematosus: report of two cases

Autor: O N Manousos, Ioannis E. Koutroubakis, Stilianos M. Spanoudakis, Herakles Kritikos, Efthimia Petinaki, Andreas N. Kapsoritakis, Ioannis A. Mouzas, Elias A. Kouroumalis
Rok vydání: 1998
Předmět:
Zdroj: Europe PubMed Central
ISSN: 0954-691X
Popis: Background Common aetiopathogenic factors may explain the association of ulcerative colitis with autoimmune disorders such as systemic lupus erythematosus. Patients We report two cases of ulcerative colitis associated with idiopathic systemic lupus erythematosus: one patient who developed ulcerative colitis 11 years after having been diagnosed as a case of systemic lupus erythematosus and one case of simultaneous appearance of the two diseases. The lupus clinical manifestations were in neither case correlated with the treatment of ulcerative colitis. Conclusion The association between ulcerative colitis and systemic lupus erythematosus is rare. Although a chance occurrence cannot be excluded it is possible that both conditions share some genetic or immunological defects.
Databáze: OpenAIRE