Chikungunya disease among infants in French West Indies during the 2014 outbreak
| Autor: | F. Delion, B. Muanza, Arthur Gavotto, J.-A. Dusacre, Pascal Amedro |
|---|---|
| Přispěvatelé: | Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), University Hospital, University Hospital , Pointe-à-Pitre, Guadeloupe, Laboratoire de Neurosciences Fonctionnelles et Pathologies (LNFP), Université de Lille, Droit et Santé-Centre National de la Recherche Scientifique (CNRS), University Hospital, Pointe-à-Pitre, Guadeloupe., Physiologie & médecine expérimentale du Cœur et des Muscles [U 1046] (PhyMedExp), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), MORNET, Dominique |
| Rok vydání: | 2017 |
| Předmět: |
Tachycardia
Male Pediatrics medicine.medical_specialty Fever viruses [SDV]Life Sciences [q-bio] education Disease medicine.disease_cause Disease Outbreaks 03 medical and health sciences 0302 clinical medicine Monocytosis 030225 pediatrics Edema Febrile seizure parasitic diseases French West Indies medicine Humans Chikungunya Prospective Studies Guadeloupe health care economics and organizations Arbovirus business.industry Outbreak virus diseases Infant medicine.disease 3. Good health [SDV] Life Sciences [q-bio] Hospitalization Cross-Sectional Studies Child Preschool Pediatrics Perinatology and Child Health Chikungunya Fever Female medicine.symptom business Foot (unit) |
| Zdroj: | Archives de Pédiatrie Archives de Pédiatrie, 2019, ⟨10.1016/j.arcped.2019.05.014⟩ Archives de Pédiatrie, Elsevier, 2019, ⟨10.1016/j.arcped.2019.05.014⟩ |
| ISSN: | 1769-664X 0929-693X |
| Popis: | Background We aimed to describe the clinical and laboratory features of Chikungunya disease in infants aged from 1 month to 2 years. Methods This epidemiologic study was carried out at the Pointe-a-Pitre University Hospital from May to September 2014. We collected data prospectively from infants hospitalized for Chikungunya disease. Results A total of 154 infants were included. Hyperthermia was greater than 38.5 °C the first 48 h and during on average 2.7 days. Pain (on mobilization and/or cutaneous hyperesthesia and/or arthralgia) was present in 82% of the cases. Loss of appetite was reported for 62% of the infants. Initial maculopapular erythematous eruption occurred in 69% of the cases. A vesiculobullous eruption was secondarily observed in 7% of the cases. Edema on the feet and/or hands was present in 48% of the cases. Febrile seizure was observed in 12% of the cases. Lymphopenia was the most frequent laboratory finding, present in 94% of the infants. No cases of thrombocytopenia were observed. The reported complications were: bullous epidermolysis, state of epilepticus, and severe acute hepatitis. Conclusion This study highlights a suggestive clinical presentation of Chikungunya diseases combining pain, fever, tachycardia, foot and/or hand edema. Lymphopenia, monocytosis, and the absence of thrombocytopenia were relevant biological signs. |
| Databáze: | OpenAIRE |
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