Toxins and virulence factors of enterotoxigenic Escherichia coli associated with strains isolated from indigenous children and international visitors to a rural community in Guatemala
| Autor: | August L. Bourgeois, Gudrun Wiklund, Lemus O, González W, Torres Or, Ann-Mari Svennerholm, David A. Sack, Matute Ja, Pratdesaba Ra |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Adult
Diarrhea Rural Population Epidemiology Virulence Factors education enteric bacteria Bacterial Toxins Virulence Enteric bacteria Enterotoxin Biology medicine.disease_cause Indigenous Microbiology Enterotoxins Population Groups Enterotoxigenic Escherichia coli medicine Escherichia coli Humans Colonization Gastrointestinal Infections Escherichia coli Infections Travel Rural community Escherichia coli Proteins Infant Guatemala Original Papers travellers' infection Diarrhoea Infectious Diseases Child Preschool enterotoxin |
| Zdroj: | Epidemiology and Infection |
| ISSN: | 1469-4409 0950-2688 |
| Popis: | SUMMARYDiarrhoea remains a common cause of illness in Guatemala, with children suffering most frequently from the disease. This study directly compared the frequency, enterotoxin, and colonization factor (CF) profiles of enterotoxigenicEscherichia coli(ETEC) strains isolated from children living in a rural community in Guatemala and from Western visitors to the same location during the same seasons, using similar detection methodologies. We found that ETEC accounted for 26% of severe cases of diarrhoea in children requiring hospitalization, 15% of diarrhoea in the community, and 29% of travellers' diarrhoea in visitors staying ⩾2 weeks. The toxin and CF patterns of the ETEC strains isolated from both groups differed significantly (P< 0·0005) as determined byχ2= 60·39 for CFs andχ2= 35 for toxins, while ETEC phenotypes found in Guatemalan children were comparable to those found in children from other areas of the world. |
| Databáze: | OpenAIRE |
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