Formulation and Evaluation of Herbal Anti- inflammatory Lollipop using Sterculia Lychnophora Seed Extract

Autor: Shalini Dhawale, Rajkumar Moon, Pavan Birgad, Ujwala Salve, Pratiksha Bhajikhaye, Dipali Korde, Vishal Pagare, Suraj Thakare
Rok vydání: 2023
Předmět:
DOI: 10.5281/zenodo.8103970
Popis: We are moving away from nature as our lifecycle becomes more technologically savvy. Herbs are natural items, thus they have no negative side effects and are also relatively safe, environmentally friendly, and locally accessible. In many of the pathological conditions like mouth ulcers, throat infection, cough etc, it needs to localize the medicament in the oral cavity region. Considering these facts present study aims to formulate and evaluate herbal lollipop using Sterculia Lychnophora seed extract for anti-inflammatory activity. The advantages of the current study effort include higher oral dosage form bioavailability and retention time, as well as a decrease in stomach discomfort due to first pass metabolism. The conventional dosage forms like tablets and capsules, syrups etc are inconvenient for paediatric patients because of difficult to swallow tablets and capsules or unpleasant taste of drug. As a result demand for developing new technologies has been increasing day by day. In the present investigation herbal lollipop containing Sterculia Lychnophora seed extract were prepared by heating and congealing technique. For drug analysis, many instrumental techniques such as UV, FTIR, and others were used. The generated lollipop formulations were tested for thickness, weight variation, friability, hardness, stability studies, and anti- inflammatory efficacy.
Databáze: OpenAIRE