Extremely Locally Advanced Ovarian Malignant Mixed Mullerian Tumor in 37-Years-Old Female
Autor: | Margarita Peneva, Gjorgji Jota, Zoran Karadzov, Vesna Jovanovska-Manevska, Redzep Selmani, Radomir Gelevski, Magdalena Genadieva-Dimitrova |
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Rok vydání: | 2017 |
Předmět: |
Adult
medicine.medical_specialty Adjuvant chemotherapy Locally advanced Mixed Tumor Mullerian Abdominal wall Quadrant (abdomen) Carcinosarcoma Ovarian carcinoma Biopsy Medicine Humans Neoplasm Invasiveness Ovarian Neoplasms medicine.diagnostic_test business.industry Cytoreduction Surgical Procedures medicine.disease Ovarian Malignant Mixed Mullerian Tumor Tumor Burden medicine.anatomical_structure Treatment Outcome Chemotherapy Adjuvant Female Radiology business |
Zdroj: | Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki). 38(1) |
ISSN: | 1857-9345 |
Popis: | Ovarian carcinosarcomas, rare variant of ovarian carcinoma, composed of both carcinomatous and mesenchymal components, solid and/or cystic, fleshy and hemorrhagic, frequently spreading beyond the ovary, are treated with surgery and adjuvant chemotherapy according to the treatment principles of ovarian carcinomas due to the small number of reported cases and lack of randomized studies. We report a case of a 37-year-old woman with clinical signs of extremely locally advanced tumor of ovarian origin, infiltrating the lower left quadrant of the abdominal wall with necrosis of the covering skin. Prior biopsy of the left ovary and omentum confirmed poorly differentiated serous adenocarcinoma. Bulky tumor the size of a child’s head, originating from the left ovary and infiltrating into the lower left quadrant abdominal wall was debulked with wide excision of the abdominal wall and creation of wide defect of the lower left part of abdominal wall covered with Dexon mesh. After the recovery, the medial part of the defect with exposed mesh was closed with pedicled tensor fasciae latae fasciomyocutaneous flap, while the lateral part of the defect was covered with split thickness skin graft. Optimal surgical cytoreduction and adjuvant chemotherapy in case of extremely locally advanced ovarian malignant Müllerian tumor provide satisfactory recurrence-free survival period. |
Databáze: | OpenAIRE |
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