Whole-body vibration mediates mechanical hypersensitivity through Aβ-fiber and C-fiber thermal sensation in a chronic pain model
| Autor: | Anelise Sonza, Matilde Achaval, Danúbia da Cunha de Sá-Caputo, Luiza Raulino de Oliveira, Mario Bernardo-Filho, Milton Antonio Zaro, Luciana Sayuri Sanada |
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| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Male medicine.medical_specialty Sensation Thermal sensation Vibration General Biochemistry Genetics and Molecular Biology 03 medical and health sciences 0302 clinical medicine Physical medicine and rehabilitation medicine Hypersensitivity Pressure Whole body vibration Animals Fiber Rats Wistar Original Research Nerve Fibers Unmyelinated business.industry Chronic pain Temperature medicine.disease Disease Models Animal 030104 developmental biology Touch Nociceptor Chronic Pain business 030217 neurology & neurosurgery |
| Zdroj: | Exp Biol Med (Maywood) |
| ISSN: | 1535-3699 |
| Popis: | Whole-body vibration (WBV), which is widely used as a type of exercise, involves the use of vibratory stimuli and it is used for rehabilitation and sports performance programmes. This study aimed to investigate the effect of WBV treatment in a chronic pain model after 10 WBV sessions. An animal model (chronic pain) was applied in 60 male Wistar rats (±180 g, 12 weeks old) and the animals were treated with low intensity exercise (treadmill), WBV (vibrating platform), and a combined treatment involving both. The controls on the platform were set to a frequency of 42 Hz with 2 mm peak-to-peak displacement, g ≈ 7, in a spiral mode. Before and after the vibration exposure, sensitivity was determined. Aβ-fibers-mediated mechanical sensitivity thresholds (touch-pressure) were measured using a pressure meter. C-fibers-mediated thermal perception thresholds (hot pain) were measured with a hot plate. After each session, WBV influenced the discharge of skin touch-pressure receptors, reducing mechanical sensitivity in the WBV groups ( P |
| Databáze: | OpenAIRE |
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