Indium 111-labeled granulocyte scan in the diagnosis and management of acute inflammatory bowel disease
| Autor: | Herand Abcarian, Dan G. Pavel, Arunas Gasparaitis, Kodanallur S. Subramanian, Richard L. Nelson |
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| Rok vydání: | 1990 |
| Předmět: |
Male
medicine.medical_specialty Radiography Scintigraphy Inflammatory bowel disease medicine Methods Humans Colitis Radionuclide Imaging medicine.diagnostic_test business.industry Indium Radioisotopes Gastroenterology General Medicine medicine.disease Inflammatory Bowel Diseases Colorectal surgery Endoscopy Erythrocyte sedimentation rate Acute Disease Histopathology Female Radiology Nuclear medicine business Granulocytes |
| Zdroj: | Diseases of the colon and rectum. 33(6) |
| ISSN: | 0012-3706 |
| Popis: | The indium 111 granulocyte scan was used to evaluate 39 individuals known to have or suspected of having inflammatory bowel disease. Twenty-three of these individuals had positive scans and 16 had negative scans. Eighty-seven confirmatory studies, which consisted of barium radiography, endoscopy, operative findings, and histopathology, were performed in 37 of these individuals. The remaining two negative scans corroborated only by clinical course, CBC, and erythrocyte sedimentation rate. In addition, 10 follow-up scans were performed in six of the 39 patients to monitor therapy or investigate a change in symptoms. As an anatomic indicator of acute granulocytic infiltration of the intestinal lamina propria and crypts, the authors found that this scan had a 97 percent rate of sensitivity and 100 percent specificity. Specific indications for the use of the indium 111-labeled granulocyte scan are described. For the authors, in general, this test has become a vital adjunct to endoscopy and radiography in the diagnosis and management of patients with symptoms of inflammatory bowel disease. |
| Databáze: | OpenAIRE |
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