A new pair of CR1-like LINE and tRNA-derived SINE elements in Podarcis sicula genome
| Autor: | Monica Rienzo, Consiglia Russo, Patrizia Palomba, Giovanni Pontecorvo, Stefania Fantaccione |
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| Rok vydání: | 2004 |
| Předmět: |
Untranslated region
Interspersed repeat Molecular Sequence Data Retrotransposon Biology Genome RNA Transfer Genetics Animals Sine Repeated sequence Short Interspersed Nucleotide Elements Binding Sites Base Sequence Lizards General Medicine DNA Sequence Analysis DNA Long terminal repeat Long interspersed nuclear element Mutagenesis Insertional Long Interspersed Nucleotide Elements RNA Transfer Lys Sequence Alignment |
| Zdroj: | Gene. 339 |
| ISSN: | 0378-1119 |
| Popis: | We have identified and characterized a new pair of LINE and SINE elements, called Lucy-1 CR1-like LINE and P.s.1/SINE, respectively, in Podarcis sicula genome. The 3′-tail region in the 3′ untranslated region (UTR) of Lucy-1 element is almost identical to the of P.s.1/SINE element. This identity suggests that the P.s.1/SINE element, during evolution, has gained the 3′-end sequence of the Lucy-1 element and has exclusively recruited the enzymatic machinery of its partner CR1 LINE for retroposition. Moreover, the complex molecular organization around Lucy-1 insertion site is discussed and we found that Lucy-1 insertion is associated with the calcium binding transporter gene. Our results confirm that the retrotransposons can be an additional source of genomic diversification and the evolution of the retrotransposable elements can be a vector force shaping genomes by reassorting DNA domains thus forming a new DNA arrangement. |
| Databáze: | OpenAIRE |
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