The Accuracy of the Increased Prostate Specific Antigen Level (Greater than or Equal to 20 Ng./Ml.) in Predicting Prostate Cancer: Is Biopsy Always Required?
| Autor: | Nehemia Hampel, Allen D. Seftel, Robert E. Gerstenbluth, Martin I. Resnick, Michael G. Oefelein |
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| Rok vydání: | 2002 |
| Předmět: |
Gynecology
medicine.medical_specialty Prostate biopsy medicine.diagnostic_test business.industry Urology Cancer urologic and male genital diseases medicine.disease Ultrasound-Guided Prostate Biopsy Prostate-specific antigen Prostate cancer medicine.anatomical_structure Prostate Predictive value of tests Biopsy medicine business |
| Zdroj: | Journal of Urology. 168:1990-1993 |
| ISSN: | 1527-3792 0022-5347 |
| DOI: | 10.1016/s0022-5347(05)64279-6 |
| Popis: | Purpose: Urologists are often referred patients who initially present with an extremely high serum prostate specific antigen (PSA) level. Despite a presumptive diagnosis of prostate cancer, many of these men undergo biopsy to obtain a tissue diagnosis before treatment with androgen ablative therapy. We examined a data base of men undergoing prostate biopsy to determine the accuracy of high PSA levels (greater than or equal to 20 ng./ml.) in predicting prostate cancer.Materials and Methods: We reviewed the records of 1,250 consecutive patients undergoing transrectal ultrasound guided prostate biopsy at 1 institution. From this data base we identified all patients with PSA greater than or equal to 20 ng./ml. at the time of prostate biopsy. The accuracy of PSA in predicting cancer was determined by calculating positive predictive values for PSA ranges and PSA cutoffs.Results: We identified 187 men (15%) presenting with PSA greater than or equal to 20 ng./ml. Of these 187 men 157 (84.0%) were diagnose... |
| Databáze: | OpenAIRE |
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