Efficacy of sodium bentonite as a detoxifier of broiler feed contaminated with aflatoxin and fumonisin
| Autor: | R. D. Miazzo, S. Ferrero, M. Salvano, Eulógio Carlos Queiroz de Carvalho, María F. Peralta, Stella Maris Chiacchiera, Carina Elizabeth Magnoli, Carlos Alberto da Rocha Rosa, Ana Maria Dalcero |
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| Rok vydání: | 2005 |
| Předmět: |
Aflatoxin
Aflatoxin B1 Globulin Animal feed Food Contamination Fumonisins Intestinal absorption chemistry.chemical_compound Animal science Animals Gizzard Poultry Diseases Fumonisin B1 biology Liver Diseases Albumin Broiler Organ Size General Medicine Animal Feed Diet Intestinal Absorption Liver chemistry Biochemistry Bentonite biology.protein Animal Science and Zoology Chemical and Drug Induced Liver Injury Chickens |
| Zdroj: | Poultry Science. 84:1-8 |
| ISSN: | 0032-5791 |
| DOI: | 10.1093/ps/84.1.1 |
| Popis: | Sodium bentonite (SB) was evaluated for its ability to reduce the deleterious effects of fumonisin B1 (FB1) and aflatoxin B1 (AFB1) in broiler diets. It was incorporated into the diets (0.3%) containing 2.5 mg/kg AFB1, 200 mg/kg FB1, or a combination of 2.5 mg/kg AFB1 and 200 mg/kg FB1. Aflatoxin B1 significantly diminished body weight gain, whereas FB1 or the combination of FB1 and SB had no effect. Addition of SB in the diets significantly diminished the inhibitory effects of dietary AFB1. Feeding AFB1 alone caused significant increases in the relative weights of most observed organs. Feeding FB1 alone did not alter relative weights of any organs. In the combined diet (AFB1 plus FB1) relative weights of the liver, kidney, gizzard, and spleen were increased. Addition of SB to the diet containing AFB1 diminished the relative weights of liver, kidney, and spleen. Addition of SB to diets containing AFB1 and FB1 only decreased liver weights. In relation to the control, lower serum levels of total protein, albumin, and globulins were observed for all AFB, containing diets without SB addition, whereas all other treatments were not altered. Livers of birds fed diets containing AFB1 and a combination of AFB1 and FB1 were enlarged, yellowish, friable, and had rounded borders. The histopathology of them, stained with hematoxylin and eosin, showed multifocal and varied cytoplasmatic vacuolization with perilobular location. Incorporation of SB reduced the incidence and severity of the hepatic histopathology changes associated with aflatoxicosis. |
| Databáze: | OpenAIRE |
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