Comparative genome analysis provides novel insight into the interaction of Aquimarina sp. AD1, BL5 and AD10 with their macroalgal host
| Autor: | Vipra Kumar, Jennifer L. Hudson, Suhelen Egan |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0106 biological sciences
food.ingredient Gliding motility Virulence Aquatic Science Biology 010603 evolutionary biology 01 natural sciences Genome 03 medical and health sciences food Symbiosis Genetics Microalgae Gene 030304 developmental biology 0303 health sciences Aquimarina Strain (biology) Genomics Vitamin biosynthesis Host-Pathogen Interactions Rhodophyta Flavobacteriaceae |
| Zdroj: | Marine genomics. 46 |
| ISSN: | 1876-7478 |
| Popis: | The Aquimarina genus is widely distributed throughout the marine environment, however little is understood regarding its ecological role, particularly when in association with eukaryotic hosts. Here, we examine the genomes of two opportunistic pathogens, Aquimarina sp. AD1 and BL5, and a non-pathogenic strain Aquimarina sp. AD10, that were isolated from diseased individuals of the red alga Delisea pulchra. Each strain encodes multiple genes for the degradation of marine carbohydrates and vitamin biosynthesis. These traits are hypothesised to promote nutrient exchange between the Aquimarina strains and their algal host, facilitating a close symbiotic relationship. Moreover, each strain harbours the necessary genes for the assembly of a Type 9 Secretion System (T9SS) and the associated gliding motility apparatus. In addition to these common features, pathogenic strains AD1 and BL5, encode genes for the production of flexirubin type pigments and a number of unique non-ribosomal peptide synthesis (NRPS) gene clusters, suggesting a role for these uncharacterised traits in virulence. This study provides valuable insight into the potential ecological role of Aquimarina in the marine environment and the complex factors driving pathogenesis and symbiosis in this genus. |
| Databáze: | OpenAIRE |
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