Nucleated red blood cells as predictor of all-cause mortality in emergency department
| Autor: | Mehmet Murat Oktay, Cüneyt Ayrık, Mehmet Burak Yavuz Çimen, Hüseyin Narcı |
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| Přispěvatelé: | HKÜ, Meslek Yüksekokulu, İlk ve Acil Yardım Programı |
| Rok vydání: | 2021 |
| Předmět: |
Male
Risk medicine.medical_specialty Erythroblasts Logistic regression 03 medical and health sciences 0302 clinical medicine Primary outcome Nucleated red blood cells Predictive Value of Tests Internal medicine medicine Humans Hospital Mortality Mortality Aged Retrospective Studies Emergency department business.industry Nucleated Red Blood Cell 030208 emergency & critical care medicine General Medicine Odds ratio Prognosis Confidence interval Logistic analysis Erythrocyte Count Emergency Medicine Female Emergency Service Hospital business All cause mortality |
| Zdroj: | The American Journal of Emergency Medicine. 46:335-338 |
| ISSN: | 0735-6757 |
| DOI: | 10.1016/j.ajem.2020.10.002 |
| Popis: | Bacground: Nucleated red blood cells (NRBCs) are immature erythrocytes that are not normally detected in the blood of healthy adults. The detection of these cells in peripheral blood is associated with increased mortality and poor prognosis. In this study, we aimed to investigate whether NRBCs predict for all causes of death in patients admitted to the emergency department (ED). Method: This study was conducted retrospectively between January 2019 and December 2019 in academic emergency department, faculty of medicine. We included all patients who died of non-traumatic causes and The control group consisted of patients discharged from the ED. NRBCs and other laboratory parameters were compared between the two groups. The primary outcome is all-cause mortality in the ED. Multivariate logistic analysis was performed. Results: A total of 204 patients (119 male) were included in the study. The mean age of the patients was 66.7 ± 14.6 years. NRBC value was higher in those who died (678.43 ± 655.16/ μl) compared to the control group (22.55 ± 57.86/ μl) (P < 0.001). According to receiver operating characteristic curve analysis (ROC) performed for the prediction all cause mortality in the ED, the best cut-off point for NRBC was >0 /μl (sensitivity 94,12%, specificity 82,35%, Area Under Curve (AUC) =0.97). In the multivariate logistic regression analysis, the NRBC was associated with all-cause mortality in the ED (odds ratio,OR = 1.020, confidence interval, CI = 1.012–1.028). Conclusıons: High blood levels of nucleated red blood cells at admission to the emergency department may be associated with increased mortality. © 2020 Elsevier Inc. |
| Databáze: | OpenAIRE |
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