Craniospinal irradiation using a forward planned segmented field technique
| Autor: | J Lewis, Jennifer Wilkinson, E Murphy, H H Lucraft, G P Lawrence |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
medicine.medical_treatment
Planning target volume Field (computer science) Craniospinal Irradiation Central Nervous System Neoplasms Prone Position Medicine Humans Radiology Nuclear Medicine and imaging Cerebellar Neoplasms Spinal Neoplasms business.industry Brain Neoplasms Radiotherapy Planning Computer-Assisted Radiotherapy Dosage General Medicine Radiation therapy Prone position Tomography Particle Accelerators business Nuclear medicine Tomography X-Ray Computed Intensity modulation Craniospinal Medulloblastoma |
| Zdroj: | The British journal of radiology. 80(951) |
| ISSN: | 1748-880X |
| Popis: | Craniospinal irradiation is technically demanding due to the complex shape of the planning target volume (PTV). Radiotherapy treatment techniques have evolved over time as imaging and radiotherapy treatment technology have improved. However, most are variations on a class solution utilizing a prone patient position with two shaped lateral cranial portals and a matched posterior spinal portal with moving junctions. Major areas of difficulty remain with the accurate definition of the PTV and achieving a homogeneous dose within it, especially at the junctions. We describe a three-dimensionally (3D) planned craniospinal radiation technique that permits rapid image acquisition with reduced localization time, simplified spinal PTV definition and standardized cranial PTV definition. Improved dose homogeneity within the PTV is achieved by use of a segmented "field-in-field" technique (forward planned intensity-modulated radiotherapy (IMRT)) in place of customized compensators. This has negated the requirement for constructing physical compensators. Autosequencing for field delivery enables the junction to be "moved" during a single fraction and reduces the overall treatment time, an important consideration when treating very young patients. |
| Databáze: | OpenAIRE |
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