Accuracy of diffusion kurtosis imaging in characterization of breast lesions
| Autor: | Haralambos Bougias, Abraham Ghiatas, Konstantia Veliou, Dimitrios Priovolos, Alexandra Christou |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
medicine.medical_specialty Volume of interest Contrast Media Breast Neoplasms Sensitivity and Specificity 030218 nuclear medicine & medical imaging Diagnosis Differential 03 medical and health sciences 0302 clinical medicine Image Interpretation Computer-Assisted medicine Humans Breast MRI Effective diffusion coefficient Radiology Nuclear Medicine and imaging Breast Diffusion Kurtosis Imaging Aged Full Paper medicine.diagnostic_test business.industry Reproducibility of Results General Medicine Middle Aged Image Enhancement Diffusion Magnetic Resonance Imaging 030220 oncology & carcinogenesis Kurtosis Female Radiology Nuclear medicine business |
| Zdroj: | The British Journal of Radiology. 90:20160873 |
| ISSN: | 1748-880X 0007-1285 |
| Popis: | Objective:The aim of this study was to evaluate the accuracy of diffusion kurtosis in the characterization and differentiation of breast lesions.Methods:49 females with 53 breast lesions underwent breast MRI. The MRI magnetic field is 1.5 T, and the protocol is standard MRI sequences, dynamic sequences pre- and post-contrast agent administration and diffusion images. Diffusion kurtosis imaging (DKI) was applied as part of our standard breast MRΙ protocol. Two experienced radiologists on breast MRI, blinded to the final diagnosis, reviewed the parametric maps and placed a volume of interest on all slices including each lesion. Kurtosis [K apparent (Kapp)] and corrected apparent diffusion coefficient [D apparent (Dapp)] median values were then calculated from the whole-lesion histogram analysis. Receiver-operating characteristic analysis was used to determine the most effective cut-off values for the differentiation between benign and malignant pathologies. Histological analysis of the breast lesions was pe... |
| Databáze: | OpenAIRE |
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