Evaluation and protection of corneal endothelium
| Autor: | David B. Soll, Frank C. Arturi, Thomas Clinch, Sol E. Harrison |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Corneal endothelium
Biocompatibility Endothelium Swine In Vitro Techniques Pharmacology Umbilical cord Cornea Corneal Transplantation chemistry.chemical_compound Hyaluronic acid medicine Animals Humans Hyaluronic Acid Lenses Intraocular Staining and Labeling Chemistry Chondroitin Sulfates Albumin Serum Albumin Bovine Macaca mulatta In vitro Macaca fascicularis Ophthalmology medicine.anatomical_structure Lens (anatomy) Immunology Sharks Cattle Rabbits gamma-Globulins Chondroitin |
| Zdroj: | American Intra-Ocular Implant Society Journal. 6:239-242 |
| ISSN: | 0146-2776 |
| DOI: | 10.1016/s0146-2776(80)80068-1 |
| Popis: | Since human corneal endothelial cells are not known to reproduce, their evaluation assumes para mount importance in light of the recent increase in in traocular lens (IOL) implantation. Earlier work has been carried out in the area of protecting corneas with nonbiological l ,2 and biological polymers. :3,4 This pa per compares four substances used to protect the cor neal endothelium during lens implantation: bovine se rum albumin, human gamma globulin, umbilical cord hyaluronic acid, and shark chondroitin sulphate C. These biological macromolecules were chosen for high spatial adaptivity, responsiveness to innocuous solution additives, biocompatibility, and ability to cre ate an adjustable viscous medium. The in vitro and animal studies described herein rely on the dye exclusion technique 5 - 7 for evaluation of corneal viability. 8-10 MATERIALS AND METHODS In vitro study |
| Databáze: | OpenAIRE |
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