Incidence, management and outcome of women requiring massive transfusion after childbirth in the Netherlands: secondary analysis of a nationwide cohort study between 2004 and 2006
| Autor: | Joost J. Zwart, Dacia D. C. A. Henriquez, Paul I. Ramler, Thomas van den Akker, Jos van Roosmalen |
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| Přispěvatelé: | Athena Institute |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Adult
Maternal mortality medicine.medical_specialty Blood transfusion medicine.medical_treatment Population lcsh:Gynecology and obstetrics law.invention Cohort Studies Young Adult 03 medical and health sciences 0302 clinical medicine SDG 3 - Good Health and Well-being Pregnancy Interquartile range law Case fatality rate Humans Medicine Childbirth 030212 general & internal medicine education lcsh:RG1-991 Netherlands education.field_of_study 030219 obstetrics & reproductive medicine business.industry Obstetrics Incidence Obstetrics and Gynecology Delivery Obstetric medicine.disease Intensive care unit Postpartum hemorrhage Uterine atony Treatment Outcome Female Uterine Inertia business Research Article Maternal morbidity Cohort study |
| Zdroj: | BMC Pregnancy and Childbirth, Vol 17, Iss 1, Pp 1-8 (2017) BMC Pregnancy and Childbirth, 17 Ramler, P I, van den Akker, T, Henriquez, D D C A, Zwart, J J & van Roosmalen, J 2017, ' Incidence, management and outcome of women requiring massive transfusion after childbirth in the Netherlands : Secondary analysis of a nationwide cohort study between 2004 and 2006 ', BMC Pregnancy and Childbirth, vol. 17, 197, pp. 1-8 . https://doi.org/10.1186/s12884-017-1384-7 BMC Pregnancy and Childbirth BMC Pregnancy and Childbirth, 17(1), 197-205. BioMed Central BMC Pregnancy and Childbirth, 17:197, 1-8. BioMed Central |
| ISSN: | 1471-2393 |
| Popis: | Background Postpartum hemorrhage remains the leading cause of maternal morbidity and mortality worldwide. Few population-based studies have examined the epidemiology of massive transfusion for postpartum hemorrhage. The aim of this study was to determine the incidence, management, and outcomes of women with postpartum hemorrhage who required massive transfusion in the Netherlands between 2004 and 2006. Methods Data for all women from a gestational age of 20 weeks onwards who had postpartum hemorrhage requiring eight or more red blood cell concentrates were obtained from a nationwide population-based cohort study including all 98 hospitals with a maternity unit in the Netherlands. Results Three hundred twenty-seven women who had postpartum hemorrhage requiring massive transfusion were identified (massive transfusion rate 91 per 100,000 deliveries (95% confidence interval: 81–101)). The median blood loss was 4500 mL (interquartile range 3250–6000 mL) and the median number of red blood cell concentrates transfused was 11 units (interquartile range 9–16 units). Among women receiving massive transfusion, the most common cause of hemorrhage was uterine atony. Eighty-three women (25%) underwent hysterectomy, 227 (69%) were admitted to an intensive care unit, and three women died (case fatality rate 0,9%). Conclusion The number of women in the Netherlands who had postpartum hemorrhage treated with massive transfusion was relatively high compared to other comparable settings. Evidence-based uniform management guidelines are necessary. Electronic supplementary material The online version of this article (doi:10.1186/s12884-017-1384-7) contains supplementary material, which is available to authorized users. |
| Databáze: | OpenAIRE |
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