Hypergammaglobulinemic Purpura of Waldenström: Characterization of Circulating Immune Complexes
| Autor: | Fulvio Invernizzi, F. Pitingolo, C. Granatieri, G. Serino, C. Zara, Carlo Zanussi, V. Maresca |
|---|---|
| Rok vydání: | 1983 |
| Předmět: |
Adult
Male Immunodiffusion Antigen-Antibody Complex Immune system Rheumatoid Factor medicine Humans business.industry Hypergammaglobulinemia Complement System Proteins Purpura Hyperglobulinemic Hematology General Medicine Middle Aged medicine.disease Immunoglobulin A Purpura Immunoglobulin M Immunoglobulin G Immunology Chromatography Gel Female medicine.symptom business Ultracentrifugation |
| Zdroj: | Acta Haematologica. 69:152-157 |
| ISSN: | 1421-9662 0001-5792 |
| DOI: | 10.1159/000206881 |
| Popis: | Circulating immune complexes were detected in the sera of 7 patients with hypergammaglobulinemic purpura of Waldenström by the following methods: KgB-SP, mRF-LIA, Cc test, ClqBA. Analytical ultracentrifugation showed intermediate complexes between 7S and 19S (16S-19S); simple immunodiffusion of the complexes, purified by 2.5% PEG precipitation, revealed the presence of IgG3, IgA, IgM, Clq, C3 and C4. Constant high titers of rheumatoid activity in the sera in toto and after purification, and normal serum complement levels were also detected. |
| Databáze: | OpenAIRE |
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