The outcome of a national MS-Covid-19 study: What the Turkish MS cohort reveals?
| Autor: | M. P. Sormani, Cihat Uzunköprü, Murat Terzi, Husnu Efendi, Haluk Gümüş, Aslı Tuncer, Aksel Siva, Luca Carmisciano, Tuncay Gündüz, Melih Tutuncu, Ugur Uygunoglu, N. Kale Icen, Sedat Sen, Ömer Faruk Turan, Cavid Baba, Pinar Acar, Serkan Ozakbas, B. Petek Balci, Mesrure Koseoglu, Rana Karabudak, I. Gungor Dogan, Mehmet Fatih Yetkin, Irene Schiavetti, Semra Demir |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
medicine.medical_specialty Multiple Sclerosis Population Disease Article Cohort Studies 03 medical and health sciences 0302 clinical medicine Disease modifying treatment Internal medicine medicine Humans 030212 general & internal medicine education Case report form Disease severity education.field_of_study business.industry Fingolimod Hydrochloride SARS-CoV-2 Incidence (epidemiology) COVID-19 General Medicine medicine.disease Coronavirus Female Fingolimod Comorbidity Multiple-Sclerosis Neurology Cohort Neurology (clinical) business Rituximab 030217 neurology & neurosurgery Cohort study medicine.drug |
| Zdroj: | Multiple Sclerosis and Related Disorders |
| ISSN: | 2211-0356 2211-0348 |
| Popis: | Background: The pandemic of the new type of corona virus infection 2019 [Covid-19] also affect people with Multiple Sclerosis (pwMS). Currently, the accumulating information on the effects of the infection regarding the & nbsp;& nbsp;demographic and clinical characteristics of the disease, as well as outcomes within different DMTs & cedil; enable us to have better practices on the management of the Covid-19 infection in pwMS. Objective: To investigate the incidence of coronavirus disease 2019 (Covid-19) and to reveal the relationship between the demographic-clinical and therapeutic features and the outcome of Covid-19 infection in a multi- center national cohort of pwMS.& nbsp; Methods: The Turkish Neurological Society-MS Study Group in association with the Italian MuSC-19 Study Group initiated this study. A web-based electronic Case Report Form (eCRF) of Study-MuSC-19 were used to collect the data. The demographic data and MS histories of the patients were obtained from the file tracking forms of the relevant clinics.& nbsp; Results: 309 MS patients with confirmed Covid-19 infection were included in this study. Two hundred nineteen (219) were females (70.9%). The mean age was 36.9, ranging from 18 to 66, 194 of them (62.8%) were under 40. The clinical phenotype was relapsing-remitting in 277 (89.6%) and progressive in 32 (10.4%). Disease duration ranged from 0.2 years to 31.4 years. The median EDSS was 1.5, ranging from 0 to 8.5. The EDSS score was |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect