Experiments in Searching Small Proteins in Unannotated Large Eukaryotic Genomes

Autor:	Pierre-Antoine Rey, Samia Reffas, Anne Niknejad, Isabelle Cusin, Eve Mahe, Jacques Colinge, Lydie Bougueleret, Hassan Mattou, Marc Moniatte
Rok vydání:	2005
Předmět:	Adult Proteomics Genetics Intron Genomics Exons General Chemistry Computational biology Biology Biochemistry Genome Introns Mass Spectrometry Exon Pregnancy Humans Female Human genome Amino Acid Sequence Databases Protein Peptides Gene Peptide sequence
Zdroj:	Journal of Proteome Research. 4:167-174
ISSN:	1535-3907 1535-3893
DOI:	10.1021/pr049811i
Popis:	There is growing interest to use mass spectrometry data to search genome sequences directly. Previous work by other authors demonstrated that this approach is able to correct and complement available genome annotations. We discuss the practical difficulty of searching large eukaryotic genomes with peptide ion trap tandem mass spectra of small proteins (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87377126042fbbbcb514444402de52d1 https://doi.org/10.1021/pr049811i Zobrazit plný text záznamu