Amniotic fluid embolism-risk factors, maternal and neonatal outcomes
| Autor: | Dimitrios Mastrogiannis, Neetu J. Jain, Isha Puri, Lakota Kruse, Michail Spiliopoulos, Vani Dandolu |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
Embolism Amniotic Fluid medicine.medical_specialty Adolescent medicine.medical_treatment Mothers Infant Newborn Diseases Young Adult Amniotic fluid embolism Pregnancy Risk Factors Prevalence medicine Humans Caesarean section Maternal-Fetal Exchange Eclampsia Placental abruption Obstetrics business.industry Infant Newborn Pregnancy Outcome Obstetrics and Gynecology Middle Aged Stepwise regression medicine.disease Obstetric Labor Complications Placenta previa Embolism Pediatrics Perinatology and Child Health Female Morbidity business |
| Zdroj: | The Journal of Maternal-Fetal & Neonatal Medicine. 22:439-444 |
| ISSN: | 1476-4954 1476-7058 |
| DOI: | 10.1080/14767050902787216 |
| Popis: | To investigate demographic characteristics, risk factors, maternal and neonatal outcomes of all cases of amniotic fluid embolism that occurred in New Jersey during 1997-2005.Information was derived from a perinatal linked dataset provided by the MCH-Epidemiology Program in the New Jersey Department of Health. Bivariate analysis for dichotomous variables used the Chi-square test. Stepwise logistic regression models were created to assess the influence of potential risk factors and p value0.05 considered statistically significant.Forty-five cases of amniotic fluid embolism were identified among 1,004,116 deliveries, for a prevalence rate of 1 in 22,313 pregnancies. Statistically, significant association was found with multifetal pregnancy, caesarean section, placenta previa, placental abruption, eclampsia and cervical laceration. The rate of maternal complications such as coagulopathy, seizures, neurological damage, shock and cardiac arrest were significantly greater in the cases as compared with the overall study population. Neonatal morbidity was significant as demonstrated by higher NICU admissions and neonatal intubation rates and lower 5-min Apgar scores.Significant correlation was identified between historically reported risk factors and amniotic fluid embolism. The fetal and maternal mortality rates were lower compared with previous studies, attributed both to improvements in perinatal healthcare and reporting of 'milder' cases. |
| Databáze: | OpenAIRE |
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