Double-blind, controlled trial of short-term prednisone therapy in immunoglobulin A glomerulonephritis
| Autor: | Elizabeth Shely, Cheryl Fryer, David P. Witte, Monica Quinlan, Thomas R. Welch |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Immunoglobulin A
Male medicine.medical_specialty Adolescent medicine.drug_class Placebo Gastroenterology law.invention Nephropathy Randomized controlled trial Double-Blind Method Prednisone law Internal medicine medicine Humans Child Hematuria biology business.industry Glomerulonephritis Glomerulonephritis IGA medicine.disease Crossover study Proteinuria Treatment Outcome Creatinine Pediatrics Perinatology and Child Health Immunology biology.protein Corticosteroid Female business medicine.drug |
| Zdroj: | The Journal of pediatrics. 121(3) |
| ISSN: | 0022-3476 |
| Popis: | Twenty children and adolescents with IgA glomerulonephritis were enrolled in a crossover trial. Each received 12 weeks of prednisone therapy and 12 weeks of placebo dosing. Urinary protein and erythrocyte excretion were monitored during both courses. There was no evidence that, under the conditions of the study, corticosteroid therapy was effective in IgA nephropathy. |
| Databáze: | OpenAIRE |
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