Outcomes and complications of fetal tissue transplantation in Parkinson's disease
| Autor: | Deane B. Jacques, Thomas Carter, Oleg V. Kopyov, Abraham Lieberman, K. S. Eagle |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Fetal Tissue Transplantation
Male medicine.medical_specialty Parkinson's disease Treatment outcome Disease Brain damage Antiparkinson Agents Stereotaxic Techniques Postoperative Complications Seizures medicine Humans Surgical Wound Infection Brain Tissue Transplantation Aged Cerebral Hemorrhage Brain Diseases business.industry Cysts Incidence Parkinson Disease Middle Aged medicine.disease Combined Modality Therapy Surgery Treatment Outcome Stereotaxic technique Brain Damage Chronic Female Neurology (clinical) medicine.symptom Complication business |
| Zdroj: | Stereotactic and functional neurosurgery. 72(2-4) |
| ISSN: | 1011-6125 |
| Popis: | This study was undertaken to investigate the outcomes, complication rates and risk factors of stereotactic intrastriatal neurotransplantation for Parkinson’s disease (PD). Bilateral stereotactic neurotransplantation was performed (as previously described) in 60 patients with idiopathic PD. Clinical outcome was evaluated using the Unified Parkinson’s Disease Rating Scale (UPDRS). The incidence of complication was evaluated by retrospective analysis of the clinical outcomes of the transplanted patients. Patients demonstrated significant improvement in UPDRS scores 12 months after transplantation. Nine patients experienced adverse effects after neurotransplantation, 3 requiring surgical intervention. Patients showed a significant overall improvement and no greater incidence of risk than that of other intracranial procedures. |
| Databáze: | OpenAIRE |
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