Early-Phase Vascular Healing of Bioabsorbable vs. Durable Polymer-Coated Everolimus-Eluting Stents in Patients With ST-Elevation Myocardial Infarction ― 2-Week and 4-Month Analyses With Optical Coherence Tomography ―
| Autor: | Kazuhiro Naito, Tetsuya Amano, Shinichiro Sakurai, Hiroaki Takashima, Kenta Murotani, Akihiro Suzuki, Tadayuki Uetani, Yusuke Nakano, Akiyoshi Kurita, Katsuhisa Waseda, Masahiro Shimoda, Hirohiko Ando |
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| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment 030204 cardiovascular system & hematology 03 medical and health sciences Vascular healing 0302 clinical medicine Optical coherence tomography Neointima Internal medicine medicine Humans In patient Everolimus cardiovascular diseases 030212 general & internal medicine Myocardial infarction Stent thrombosis Thrombus Aged Wound Healing medicine.diagnostic_test business.industry Percutaneous coronary intervention Drug-Eluting Stents Thrombosis General Medicine Middle Aged equipment and supplies medicine.disease Coronary Vessels surgical procedures operative Cardiology ST Elevation Myocardial Infarction Female Cardiology and Cardiovascular Medicine business Early phase Tomography Optical Coherence |
| Zdroj: | Circulation Journal. 82:2594-2601 |
| ISSN: | 1347-4820 1346-9843 |
| DOI: | 10.1253/circj.cj-18-0230 |
| Popis: | BACKGROUND Despite the revolution of coronary stents, there remain concerns about the risk of stent thrombosis, especially in patients with ST-elevation myocardial infarction (STEMI). The present study compared early vascular healing as a contributing factor to reducing stent thrombosis between Xience everolimus-eluting stents (X-EES) and Synergy everolimus-eluting stents (S-EES) in patients with STEMI. Methods and Results: The present study included 47 patients with STEMI requiring primary percutaneous coronary intervention with X-EES (n=25) or S-EES (n=22). Optical coherence tomography (OCT) assessments of the stented lesions were performed 2 weeks and 4 months after stent implantation. Neointimal strut coverage, malapposition and the frequency of thrombus formation were evaluated. In the 2-week OCT analysis, the proportion of covered struts in S-EES (42.4±15.4%) was significantly higher than in X-EES (26.3±10.1%, P |
| Databáze: | OpenAIRE |
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