A psychometric evaluation of the Functional assessment of cancer therapy-kidney symptom index (FKSI-19) among renal cell carcinoma patients suggesting an alternative two-factor structure
Autor: | Pernilla Sundqvist, Andreas Karlsson Rosenblad, Bodil Westman, Börje Ljungberg |
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Předmět: |
Oncology
medicine.medical_specialty Psychometrics Health-related quality of life 030232 urology & nephrology Kidney Renal cancer carcinoma Article 03 medical and health sciences 0302 clinical medicine Quality of life Renal cell carcinoma Internal medicine Surveys and Questionnaires Urologi och njurmedicin medicine Urology and Nephrology Humans Psychometric analysis Carcinoma Renal Cell Cancer och onkologi Patient-reported outcomes business.industry Public Health Environmental and Occupational Health Cancer Reproducibility of Results Kidney cancer medicine.disease Exploratory factor analysis Confirmatory factor analysis Kidney Neoplasms 030220 oncology & carcinogenesis Cancer and Oncology Cohort Quality of Life Factor analysis business Factor Analysis Statistical |
Zdroj: | Andreas Karlsson Rosenblad BASE-Bielefeld Academic Search Engine Quality of Life Research |
Popis: | Purpose To psychometrically evaluate the hypothesized four-factor structure of the 19-item Functional Assessment of Cancer Therapy—Kidney Symptom Index (FKSI-19) health-related quality of life (HRQoL) instrument in a sample of surgically treated renal cell carcinoma (RCC) patients and examine if an alternative factor structure with good psychometric properties may be derived from the available items. Methods The model fit of the hypothesized four-factor structure was examined using confirmatory factor analysis on cohort data from 1731 individuals included in the National Swedish Kidney Cancer Register who had undergone surgery for RCC during the three years 2016–2018 and answered the FKSI-19 instrument within 6–12 months after surgery. Exploratory factor analysis was applied to the same dataset to derive a possible alternative factor solution. Results The four-factor structure did not reach the thresholds for good model fit using the normed χ2-value or the Comparative Fit Index, although the Standardized Root Mean Square Residual and Root Mean Square Error of Approximation measures indicated good and acceptable model fits, respectively. An alternative 14-item trimmed FKSI version (FKSI-14) with a two-factor structure derived from the available FKSI-19 items was found to measure the same aspects of HRQoL as the full FKSI-19 instrument. Conclusion The present study is the first to use psychometric methods for examining the factor structure of the FKSI-19 instrument. The hypothesized four-factor structure of FKSI-19 provided a barely acceptable model fit. The two-factor FKSI-14 structure may be used as an alternative or complement to the four-factor structure when interpreting the FKSI-19 instrument. |
Databáze: | OpenAIRE |
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