Neuroligin 1 expression is linked to plasticity of behavioral and neuronal responses to sex pheromone in the male moth Agrotis ipsilon
| Autor: | Paleo Aguilar, Elodie Demondion, Stéphane Debernard, Nicolas Durand, Françoise Bozzolan, Thomas Bourgeois |
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| Přispěvatelé: | Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Ecologie et Dynamique des Systèmes Anthropisés - UMR CNRS 7058 (EDYSAN), Université de Picardie Jules Verne (UPJV)-Centre National de la Recherche Scientifique (CNRS), Universidad Complutense de Madrid = Complutense University of Madrid [Madrid] (UCM), Institut d'écologie et des sciences de l'environnement de Paris (iEES Paris ), Institut de Recherche pour le Développement (IRD)-Sorbonne Université (SU)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
Olfactory system Physiology Cell Adhesion Molecules Neuronal Mating behavior Agrotis ipsilon Neuroligin Moth Sex pheromone Moths Aquatic Science 03 medical and health sciences 0302 clinical medicine Olfactory plasticity medicine Animals Sex Attractants Mating Molecular Biology Ecology Evolution Behavior and Systematics 030304 developmental biology Neurons 0303 health sciences biology Neuroligin 1 biology.organism_classification Antennal lobes Cell biology medicine.anatomical_structure Odor Insect Science Pheromone Female Animal Science and Zoology Antennal lobe [SDE.BE]Environmental Sciences/Biodiversity and Ecology 030217 neurology & neurosurgery |
| Zdroj: | Journal of Experimental Biology Journal of Experimental Biology, The Company of Biologists, 2021, 224 (22), ⟨10.1242/jeb.243184⟩ |
| ISSN: | 0022-0949 1477-9145 |
| DOI: | 10.1242/jeb.243184⟩ |
| Popis: | In the moth Agrotis ipsilon, the behavioral response of males to the female-emitted sex pheromone increases throughout adult life and following a prior exposure to sex pheromone, whereas it is temporally inhibited after the onset of mating. This behavioral flexibility is paralleled with changes in neuronal sensitivity to pheromone signal within the primary olfactory centers, the antennal lobes. In the present study, we tested the hypothesis that neuroligins, post-synaptic transmembrane proteins known to act as mediators of neuronal remodeling, are involved in the olfactory modulation in A. ipsilon males. We cloned a full-length cDNA encoding neuroligin 1, which is expressed predominantly in brain and especially in antennal lobes. The level of neuroligin 1 expression in antennal lobes gradually raised from day-2 until day-4 of adult life, as well as at 24 h, 48 h and 72 h following pre-exposure to sex pheromone, and the temporal dynamic of these changes correlated with increased sex pheromone responsiveness. By contrast, there was no significant variation in antennal lobe neuroligin 1 expression during the post-mating refractory period. Taken together, these results highlight that age- and odor experience-related increase in sex pheromone responsiveness is linked to the overexpression of neuroligin 1 in antennal lobes, thus suggesting a potential role played by this post-synaptic cell-adhesion molecule in mediating the plasticity of the central olfactory system in A. ipsilon. |
| Databáze: | OpenAIRE |
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