Factors associated with caregivers' underestimation of quality of life in patients with Alzheimer's disease
| Autor: | Jean-Luc Novella, Moustapha Dramé, Marie-Yvonne George, Damien Jolly, Pierre Pfitzenmeyer, Laura di Pollina, Jean-Pierre Aquino, François Blanchard, Coralie Barbe, Olivier Rouaud, Joël Ankri, Hongmei Zhao, Rachid Mahmoudi |
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| Rok vydání: | 2011 |
| Předmět: |
Gerontology
Male medicine.medical_specialty Cognitive Neuroscience Disease Comorbidity Neuropsychological Tests Quality of life (healthcare) Cognition Sex Factors Cost of Illness Alzheimer Disease Activities of Daily Living medicine Humans In patient Psychiatry Aged Aged 80 and over business.industry Depression Psychiatry and Mental health Inter-rater reliability Caregivers Data Interpretation Statistical Quality of Life Educational Status Female France Geriatrics and Gerontology business |
| Zdroj: | Dementia and geriatric cognitive disorders. 33(1) |
| ISSN: | 1421-9824 |
| Popis: | Objective: The aim of this study was to identify the factors associated with differences between how Alzheimer’s disease (AD) patients and their caregivers rate the patient’s health-related quality of life (QoL). Methods: Cross-sectional, multicentre study. Patients were 65 years or more, suffering from mild to moderate AD, native French speakers, with a main caregiver. Interrater agreement of the QoL-AD was assessed using the intraclass coefficient. A generalised linear model was used to identify factors related to the difference in health-related QoL scores between patients and their caregivers. Results: The 122 patients of the study were 82 ± 6 years old and mainly women (69%). Independent factors related to the difference between patients and caregivers were: Mini Mental State Exam score (β = 0.32; 95% CI = 0.05–0.59); instrumental activities of daily living score (β = –0.61; 95% CI = –1.14 to –0.07); total Neuropsychiatric Inventory score (β = 0.10; 95% CI = 0.05–0.59), and Zarit’s burden score (β = 0.09; 95% CI = 0.01–0.17). Conclusion: Practitioners must take into account the trend towards underestimation when health-related QoL is rated by caregivers or proxies. |
| Databáze: | OpenAIRE |
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