Acute Kidney Injury in a Patient With Cryoglobulinemia Secondary to Hepatic Mucosa-Associated Lymphoid Tissue Lymphoma: Case Report and Literature Review
| Autor: | Artsiom Klimko, Silviu-Mihai Secareanu, Nona Bejinariu, Iuliana Andreiana, Georgiana A Toma |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
membranoproliferative glomerulonephritis Renal function lymphoma 030204 cardiovascular system & hematology Gastroenterology cryoglobulinemia 03 medical and health sciences 0302 clinical medicine Internal medicine Membranoproliferative glomerulonephritis medicine Fulminant hepatitis business.industry General Engineering Acute kidney injury Hepatitis B medicine.disease Cryoglobulinemia renal involvement Lymphoma mucosa-associated lymphoid tissue Nephrology maltoma business Mucosa-associated lymphoid tissue 030217 neurology & neurosurgery |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| Popis: | We report a patient with IgM-predominant type I cryoglobulinemia (CG), who presented to our nephrology department with acute kidney injury. He was previously diagnosed with sensorimotor neuropathy, which was in remission with maintenance dose of corticosteroids. Upon admission, there were ulcerated, necrotic cutaneous lesions localized to the inner aspect of the thighs bilaterally. Further workup revealed a mucosa-associated lymphoid tissue lymphoma, causing type I CG. Screening tests for hepatitis viruses were negative at this time. Under treatment with diuretics and high-potency glucocorticoids, the patient had an acceptable recovery of renal function and was referred to oncology for treatment. Unfortunately, three months later the patient succumbed to fulminant hepatitis, presumably secondary to reactivation of an occult hepatitis B/D co-infection. We further conducted a literature review to better describe patient characteristics and renal involvement in type I CG. |
| Databáze: | OpenAIRE |
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