Effect of a miniaturized extracorporeal circulation (MECC™System) on liver function
| Autor: | Cornelius Keyl, Andreas Liebold, Christoph Wiesenack, Christopher Prasser, Alois Philipp, Magda Tenderich, Mohamed Abbady |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Indocyanine Green
Male Inotrope Extracorporeal Circulation medicine.medical_specialty Heart Diseases Cardiac index 030204 cardiovascular system & hematology Extracorporeal 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Humans Medicine Radiology Nuclear Medicine and imaging Cardiac Output Coronary Artery Bypass Aged Advanced and Specialized Nursing Liver injury business.industry Extracorporeal circulation Dye Dilution Technique General Medicine Middle Aged medicine.disease Cardiac surgery Liver 030228 respiratory system chemistry Anesthesia Female Liver function Cardiology and Cardiovascular Medicine business Safety Research Indocyanine green |
| Zdroj: | Perfusion. 22:245-250 |
| ISSN: | 1477-111X 0267-6591 |
| DOI: | 10.1177/0267659107083242 |
| Popis: | Objective: To evaluate the effect of a miniaturized extracorporeal circulation system (MECC™System) compared to conventional extracorporeal circulation (ECC) regarding liver function in cardiac surgical patients. Methods: Double indicator dilution measurements were achieved by bolus injection of indocyanine green (ICG) for assessment of cardiac index (CI) and plasma disappearance rate of ICG (PDRig). Measurements were simultaneously performed preoperatively after induction of anaesthesia (T1), following admission on the ICU (T2) and 6 h postoperatively (T3). Results: CI and PDRig were markedly increased after cardiac surgery without significant differences between groups. The percentage increase in CI was significantly correlated to the percentage increase in PDRig in both groups. Conclusion: Liver function improved after cardiac surgery in both groups of patients, which may partly be explained by an increase in CI under mild inotrope support. Differences between the extracorporeal circuits with respect to PDRig appear to be minimal in a group of patients without pre-existing liver injury. Perfusion (2007) 22, 245—250. |
| Databáze: | OpenAIRE |
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