The influence of obesity on the assessment of carotid intima-media thickness
| Autor: | Joaquín Barba, María Jesús Guembe, Pablo Irimia, Eduardo Martínez-Vila, Nerea Varo, J.J. Viñes, José M. Castellano, Jaime Gállego Pérez-Larraya, Javier Díez |
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| Rok vydání: | 2011 |
| Předmět: |
Carotid Artery Diseases
Male medicine.medical_specialty Carotid Artery Common Carotid Intima-Media Thickness Risk Assessment Statistics Nonparametric Body Mass Index Cohort Studies Sex Factors medicine.artery Internal medicine medicine Confidence Intervals Humans Radiology Nuclear Medicine and imaging cardiovascular diseases Common carotid artery Obesity Aged Ultrasonography Doppler Duplex business.industry Ultrasound Age Factors Middle Aged medicine.disease Confidence interval Surgery Atheroma Carotid Arteries Logistic Models Intima-media thickness Cardiovascular Diseases Carotid Artery External cardiovascular system Cardiology Female Internal carotid artery business Body mass index Carotid Artery Internal |
| Zdroj: | Journal of clinical ultrasound : JCU. 40(8) |
| ISSN: | 1097-0096 |
| Popis: | Background. The assessment of carotid intima-media thickness (CIMT) may improve cardiovascular risk prediction. The optimal protocol for CIMT measurement is unclear. CIMT may be measured in the common carotid artery (CCA), carotid bifurcation (CB), and internal carotid artery (ICA), but measurements from CB and ICA are more difficult to obtain. We studied the influence of body mass index (BMI) and atheroma plaques on the capacity to obtain CIMT measurements at different carotid sites. Methods. Using an automatic system, CIMT was measured in 700 subjects aged 45–75, in the near and far walls of CCA, CB, and ICA bilaterally. The presence of atheroma plaques, BMI and vascular risk factors were recorded. Results. CIMT measurements in CCA were possible in all except one subject. It was not possible to obtain CIMT measurements at CB or ICA in 24.1% of normal weight and 58.8% of obese subjects. The likelihood of obtaining CIMT measurement at all carotid sites decreased as the BMI increased. Atheroma plaques in a carotid segment did not preclude CIMT measurement at this site. Conclusions. CIMT measurements in distal carotid segments are more challenging in obese subjects. Measuring CIMT at CCA remains feasible in obese subjects and should be the primary endpoint in these subjects. Nevertheless, CB and ICA measurements, when feasible, would improve risk classification. © 2012 Wiley Periodicals, Inc. J Clin Ultrasound 40:479–485, 2012 |
| Databáze: | OpenAIRE |
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