Primary Extranodal Non-Hodgkin Lymphomas: A First Tertiary Care Experience from Punjab, North India
| Autor: | Aminder Singh, Sumit Grover, Bhavna Garg, Kunal Jain, Vikram Narang, Steffi, Harpreet Kaur, Neena Sood |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Cancer Research
medicine.medical_specialty extranodal lymphomas Tertiary care 03 medical and health sciences 0302 clinical medicine hemic and lymphatic diseases medicine Large intestine B-cell lymphoma Extranodal Involvement B cell RC254-282 0303 health sciences Gastrointestinal tract 030306 microbiology business.industry Incidence (epidemiology) india Neoplasms. Tumors. Oncology. Including cancer and carcinogens medicine.disease Dermatology Lymphoma medicine.anatomical_structure Oncology Original Article: Leukemia - Lymphoma and Myeloma 030220 oncology & carcinogenesis business |
| Zdroj: | South Asian Journal of Cancer, Vol 09, Iss 04, Pp 230-232 (2020) South Asian Journal of Cancer |
| ISSN: | 2278-4306 |
| DOI: | 10.1055/s-0041-1723073 |
| Popis: | Background Primary extranodal lymphomas are less frequently encountered and difficult to diagnose in routine practice. The histopathological and immunohistochemical studies are essential in addition to clinical details to diagnose. The incidence is varied in different parts of India along with variation in histopathological spectrum. Methodology The clinical features and histopathological findings of patients diagnosed with primary extranodal lymphoma over 3-year period were retrieved from archives of pathology department and analyzed. Results During the 3-year study period, a total of 135 cases of non-Hodgkin lymphomas were evaluated, and of these, 41.4% (56/135) of cases presented with primary extranodal involvement. The mean age of primary extranodal lymphoma presentation was 61.3 ± 17.5 with M:F ratio of 1:1.1 Most common extranodal site involved was gastrointestinal tract 32.1%, 18/56 (small intestine [17.8%, 10 cases] and large intestine [8.9%, 5 cases]). Non-Hodgkin lymphomas of B cell type were the predominant subtype (48/56, 85.7%), while 8/56 (14.2%) cases were of T cell lineage. Of the B cell non-Hodgkin lymphoma diffuse, large B cell lymphoma was the predominant subtype constituting ~83.3% (40/48). Conclusion Primary extranodal lymphomas exhibit varied histomorphological and clinical presentation. The present study is first such analysis from Punjab that intends to compare with studies from other parts of India. |
| Databáze: | OpenAIRE |
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