A Nomogram to Characterize the Severity of Detrusor Overactivity during the Ice Water Test: Description of the Method and Proof of Concept
| Autor: | André Reitz, Tanja Hüsch, Axel Haferkamp |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty genetic structures Urology Urinary Bladder 030232 urology & nephrology urologic and male genital diseases Proof of Concept Study 03 medical and health sciences 0302 clinical medicine medicine Humans Urinary Bladder Neurogenic Aged Urinary Bladder Overactive business.industry Area under the curve Reproducibility of Results Parkinson Disease Middle Aged Nomogram Ice water Nomograms Urodynamics Administration Intravesical Urinary Incontinence 030220 oncology & carcinogenesis Detrusor pressure Female business |
| Zdroj: | Urologia Internationalis. 100:294-300 |
| ISSN: | 1423-0399 0042-1138 |
| DOI: | 10.1159/000485901 |
| Popis: | Aims: To develop a nomogram with severity categories for detrusor overactivity (DO). Methods: By conducting ice water tests (IWT) in 55 patients with Parkinson’s disease, we identified criteria to describe characteristics of the detrusor pressure curves: (1) a gradient of Δpdet over Δt at the maximum detrusor pressure and (2) the area under the curve. In a nomogram, 10 severity categories of DO were established: 1 and 2 were assigned to group A (mild), 3 and 4 to group B (moderate) and 5–10 to group C (severe). Results: In the nomogram, negative IWT (20) appeared in category 1. Positive IWT (35) spread over the categories 1–8, 17 in group A, 11 in group B and 7 in categories 5–10. A relationship of incontinence episodes and nomogram category was observed. The nomogram category was reproducible in repeated IWT. Therapeutic interventions to treat DO lowered the nomogram category. Conclusion: From the relationship of detrusor pressure and time in the IWT, a nomogram with 10 severity categories of DO was developed. First observations show a relationship of nomogram category and the number of incontinence episodes, reproducibility in repeated tests and the representation of effects of therapeutic interventions to treat DO. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|