Colonic response to food in constipation
| Autor: | Pierre Arhan, Alain Faye, Philippe Le Toumelin, Michel Arsac, Ghislain Devroede, Michel Bouchoucha |
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| Rok vydání: | 2005 |
| Předmět: |
Adult
Male medicine.medical_specialty Constipation Adolescent Colon Colonic Pseudo-Obstruction Gastroenterology Descending colon Internal medicine Humans Medicine Ascending colon Ingestion Child Gastrointestinal Transit Cecum business.industry Colonic inertia digestive oral and skin physiology Rectum Infant Hindgut Fasting Middle Aged Hepatology digestive system diseases medicine.anatomical_structure Gastric Emptying Food Case-Control Studies Child Preschool Linear Models Abdomen Female France medicine.symptom business |
| Zdroj: | International Journal of Colorectal Disease. 21:826-833 |
| ISSN: | 1432-1262 0179-1958 |
| DOI: | 10.1007/s00384-005-0787-5 |
| Popis: | Colonic response to food is possibly abnormal in constipation. The colonic response to food was evaluated in 323 patients and 60 healthy subjects by following the movements of radiopaque markers after ingestion of a standard 1,000-cal test meal. Constipated patients were divided into four groups: one with a normal, and three with a delayed colorectal transit time. When the delay was found mainly in the ascending colon, the group was labeled as suffering from “colonic inertia”. In “hindgut dysfunction”, the delay was predominantly found in the descending colon, whereas the term “outlet obstruction” was reserved for constipated patients whose major site of delay was the rectosigmoid area. Colonic response to food was quantified by evaluating the variation of markers in a given abdominal region and the evolution of the geometric center on the entire plain film of the abdomen. Emptying of the caecum-ascending colon and filling of the rectosigmoid area characterize the colonic response to food in healthy subjects. Constipated patients also filled the rectosigmoid, but different patterns were found in the colon. In constipated patients with transit in the normal range, there was a frequent (41%) absence of colonic response to food as compared to controls (13%) and constipated patients with delayed transit (p |
| Databáze: | OpenAIRE |
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