Abdominal aortic aneurysm is associated with subarachnoid hemorrhage

Autor: Jeffrey L Nadel, Neeraj Chaudhary, B Thompson, Aditya S Pandey, Badih J Daou, Joseph J. Gemmete, D. Andrew Wilkinson
Rok vydání: 2020
Předmět:
Zdroj: Journal of NeuroInterventional Surgery. 13:716-721
ISSN: 1759-8486
1759-8478
DOI: 10.1136/neurintsurg-2020-016757
Popis: BackgroundAlthough intracranial aneurysms (IA) and abdominal aortic aneurysms (AAA) share similar risk factors, little is known about the relationship between them. Previous studies have shown an increased incidence of IA in patients with AAA, though the rate of subarachnoid hemorrhage (SAH) in patients with AAA has not been described.ObjectiveTo use claims data with longitudinal follow-up, to evaluate the incidence of aneurysmal SAH in patients diagnosed with AAA.MethodsWe examined longitudinally linked medical claims data from a large private insurer to determine rates of aneurysmal SAH (aSAH) and secured aSAH (saSAH) in 2004–2014 among patients with previously diagnosed AAA.ResultsWe identified 62 910 patients diagnosed with AAA and compared them 5:1 with age- and sex-matched controls. Both populations were predominantly male (70.9%), with an average age of 70.8 years. Rates of hypertension (69.7% vs 50.6%) and smoking (12.8% vs 4.1%) were higher in the AAA group (pConclusionSAH rate was elevated in patients with AAA, even after adjustment for comorbidities. Among risk factors evaluated, AAA was the strongest predictor for SAH. The relative contributions of common genetic and environmental risk factors to both diseases should be investigated.
Databáze: OpenAIRE