Elastomers in vascular tissue engineering
| Autor: | Anthony S. Weiss, Matti A. Hiob, Gareth Crouch |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Tissue Engineering
Biocompatibility Computer science 0206 medical engineering Biomedical Engineering Biocompatible Materials Bioengineering Prostheses and Implants 02 engineering and technology 021001 nanoscience & nanotechnology Elastomer 020601 biomedical engineering Article Physiological responses Blood Vessel Prosthesis Elastomers Native tissue Vascular tissue engineering Animals Blood Vessels Humans Control material 0210 nano-technology Biotechnology Biomedical engineering |
| Zdroj: | Current Opinion in Biotechnology. 40:149-154 |
| ISSN: | 0958-1669 |
| Popis: | Elastomers are popular in vascular engineering applications, as they offer the ability to design implants that match the compliance of native tissue. By mimicking the natural tissue environment, elastic materials are able to integrate within the body to promote repair and avoid the adverse physiological responses seen in rigid alternatives that often disrupt tissue function. The design of elastomers has continued to evolve, moving from a focus on long term implants to temporary resorbable implants that support tissue regeneration. This has been achieved through designing chemistries and processing methodologies that control material behavior and bioactivity, while maintaining biocompatibility in vivo. Here we review the latest developments in synthetic and natural elastomers and their application in cardiovascular treatments. |
| Databáze: | OpenAIRE |
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